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Celldex Inc rat igg2a cd27 agonist ab
(A) Splenocytes from pmel-1 mice were isolated and grown in culture in the presence of IL-2, gp100 and either monotherapy or dual therapy with MEKi and <t>CD27</t> agonist. After 4 days, cells were characterized by flow cytometry. The percentage of cells expressing (B) CD69 or (C) CD44 was quantified (n=26). P-values were calculated by a one-way ANOVA, followed by multiple comparisons testing. Error bars represent mean ± SD. *p<0.05, ****p<0.0001. (D) Representative histograms show CD69 or CD44 expression gated on lymphocytes/single cells/live cells/CD3 + CD8 + .
Rat Igg2a Cd27 Agonist Ab, supplied by Celldex Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rat+igg2a+cd27+agonist+ab/ab+antihuman+cd27+clinical+grade+varlilumab/pmc12802580-53-0-9
Average 86 stars, based on 1 article reviews
rat igg2a cd27 agonist ab - by Bioz Stars, 2026-09
86/100 stars

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1) Product Images from "Tumor site influences efficacy of MEKi and immunotherapy combinations in pre-clinical model of cholangiocarcinoma"

Article Title: Tumor site influences efficacy of MEKi and immunotherapy combinations in pre-clinical model of cholangiocarcinoma

Journal: Hepatology (Baltimore, Md.)

doi: 10.1097/HEP.0000000000001439

(A) Splenocytes from pmel-1 mice were isolated and grown in culture in the presence of IL-2, gp100 and either monotherapy or dual therapy with MEKi and CD27 agonist. After 4 days, cells were characterized by flow cytometry. The percentage of cells expressing (B) CD69 or (C) CD44 was quantified (n=26). P-values were calculated by a one-way ANOVA, followed by multiple comparisons testing. Error bars represent mean ± SD. *p<0.05, ****p<0.0001. (D) Representative histograms show CD69 or CD44 expression gated on lymphocytes/single cells/live cells/CD3 + CD8 + .
Figure Legend Snippet: (A) Splenocytes from pmel-1 mice were isolated and grown in culture in the presence of IL-2, gp100 and either monotherapy or dual therapy with MEKi and CD27 agonist. After 4 days, cells were characterized by flow cytometry. The percentage of cells expressing (B) CD69 or (C) CD44 was quantified (n=26). P-values were calculated by a one-way ANOVA, followed by multiple comparisons testing. Error bars represent mean ± SD. *p<0.05, ****p<0.0001. (D) Representative histograms show CD69 or CD44 expression gated on lymphocytes/single cells/live cells/CD3 + CD8 + .

Techniques Used: Activation Assay, Isolation, Flow Cytometry, Expressing



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Celldex Inc rat igg2a cd27 agonist ab
(A) Splenocytes from pmel-1 mice were isolated and grown in culture in the presence of IL-2, gp100 and either monotherapy or dual therapy with MEKi and <t>CD27</t> agonist. After 4 days, cells were characterized by flow cytometry. The percentage of cells expressing (B) CD69 or (C) CD44 was quantified (n=26). P-values were calculated by a one-way ANOVA, followed by multiple comparisons testing. Error bars represent mean ± SD. *p<0.05, ****p<0.0001. (D) Representative histograms show CD69 or CD44 expression gated on lymphocytes/single cells/live cells/CD3 + CD8 + .
Rat Igg2a Cd27 Agonist Ab, supplied by Celldex Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rat+igg2a+cd27+agonist+ab/ab+antihuman+cd27+clinical+grade+varlilumab/pmc12802580-53-0-9
Average 86 stars, based on 1 article reviews
rat igg2a cd27 agonist ab - by Bioz Stars, 2026-09
86/100 stars
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(A) Splenocytes from pmel-1 mice were isolated and grown in culture in the presence of IL-2, gp100 and either monotherapy or dual therapy with MEKi and CD27 agonist. After 4 days, cells were characterized by flow cytometry. The percentage of cells expressing (B) CD69 or (C) CD44 was quantified (n=26). P-values were calculated by a one-way ANOVA, followed by multiple comparisons testing. Error bars represent mean ± SD. *p<0.05, ****p<0.0001. (D) Representative histograms show CD69 or CD44 expression gated on lymphocytes/single cells/live cells/CD3 + CD8 + .

Journal: Hepatology (Baltimore, Md.)

Article Title: Tumor site influences efficacy of MEKi and immunotherapy combinations in pre-clinical model of cholangiocarcinoma

doi: 10.1097/HEP.0000000000001439

Figure Lengend Snippet: (A) Splenocytes from pmel-1 mice were isolated and grown in culture in the presence of IL-2, gp100 and either monotherapy or dual therapy with MEKi and CD27 agonist. After 4 days, cells were characterized by flow cytometry. The percentage of cells expressing (B) CD69 or (C) CD44 was quantified (n=26). P-values were calculated by a one-way ANOVA, followed by multiple comparisons testing. Error bars represent mean ± SD. *p<0.05, ****p<0.0001. (D) Representative histograms show CD69 or CD44 expression gated on lymphocytes/single cells/live cells/CD3 + CD8 + .

Article Snippet: Rat IgG2a CD27 agonist Ab (RRID: AB_3665171) was from Celldex, Inc. (Phillipsburg, NJ) under material transfer agreement.

Techniques: Activation Assay, Isolation, Flow Cytometry, Expressing